Active substances "Holoenzyme", once in the body have choleretic effect, as contained in the preparation of the digestive enzymes involved in the digestion of food and also improve the condition of the gastrointestinal tract. What constitutes a "Holenzim"? Reviews about this drug are different, but they are a little late.


This is a drug of natural origin, combined enzyme remedy, used as a choleretic and as a digestive enzyme. Constituent amylase and trypsin contribute to the digestion of proteins and carbohydrates, and also help them to be fully absorbed into the small intestine. Bile acids stimulate the formation of bile and enhance the function of the digestive tract. They also contribute to the reduction of cholesterol in the blood.

Holenzim: reviews, readings, prices and analogues

As the main tool components are:

  • the dried mucous membrane of the small intestine of cattle
  • dry bile;
  • dried and powdered pancreas.

The drug is in pill form. One of them contains 100 mg each of the active ingredients, they are coated and enclosed in different packaging: blister packs of 10 or 25 pieces (carton box can be 1, 2, 3, 4, 5 or 150), a polymer or a plastic jar of 30 or 50 pieces and strips of 10 or 25 tablets.

"Holenzim": indications and contraindications

The drug is indicated to people who have diseases or functional disorders of the gastrointestinal tract, as it has choleretic effect and acts as a digestive enzyme means. Also it can be used by persons whose digestive tract is working properly, but they have certain errors in diet, for example eat indigestible food, or do not comply with the regime. Recommended for people leading a sedentary lifestyle (including long period of immobilization) and with violations of the chewing function. General indications:

As a medicine of natural origin, he has quite a few contraindications. However, if a person has seen such conditions, you must refuse to accept "Holenzim". Counterparts will help to solve this problem (among them there are those that can be used for children up to 12 years). Contraindications include:

  • hypersensitivity to funds
  • obstructive jaundice
  • pancreatitis in an acute form
  • chronic pancreatitis in the period of exacerbation.

Side effects and interactions with other drugs

An allergic reaction is possible, which is expressed by a skin rash and hyperemia, sneezing and the flow of tears. Heartburn, an increase in transaminase blood and dyspeptic disorders suggest an overdose.

Antacids, containing magnesium hydroxide and calcium carbonate drugs reduce the effectiveness of "Holoenzyme". Meanwhile, it is combined with antiseptics and chemotherapeutics in the treatment of infectious processes in the liver and the biliary tract. Together with purgative medicine reduces the amount absorbed in the intestines of toxic substances and eliminates constipation.

"Holenzim": price and analogues

The cost of the drug depends on the manufacturer and region. On average it can range from 130 to 170 rubles. If the price is relatively low, why try to find something that will replace "Holenzim"? Reviews answer to this question is much more colorful, as many of them speak about the unbearable taste, because of which the tablet is simply impossible to swallow. This is probably one of the few cases where the counterpart searching not for high prices, but for a different reason.

It is important to know that the analogues don't always have the desired effect. Usually they all belong to one group of drugs, but the effect can manifest in different ways. If "Holenzim" was prescribed by the doctor, it is better to consult with him about the possibility of replacement of this drug by other means.

List of drugs that can replace it, great. Just need to find enzyme and cholagogue. Among them the well-known "Kreon", "Mezim", "Tykveol", "Child" and so on. However, they are more expensive, "Holoenzyme".

Whether the drug is effective?

A view of themselves deserve "Holenzim"? The reviews of those people who took the drug, not all positive, but still most of them talking about high performance tools.

About 2 weeks after you start taking passes nausea (often this symptom is that in the morning), heartburn, nagging pain in my side and abdomen. He also helps those who don't eat right and doesn't know moderation in the consumption of products. Spoken about the normalization of stools, so he is able to eliminate constipation and diarrhea. When taken regularly before meals, improved digestion and lack of heaviness in the stomach.

But there are people who are unhappy with the product. For example, they write that it helps only temporarily and does not eliminate the symptoms of indigestion. There is bad, even nauseating taste, which complicates the reception, especially for children.

Thus, the "Holenzim", which reviews are mostly positive, and has minimum side effects and natural origin. It can be concluded that the drug this deserves the attention of all who are suffering from hepatitis, cholecystitis and pancreatitis.